Preheat your oven to 350°F (175°C). Lightly grease a loaf pan or line a baking sheet with parchment paper. Preparing the pan first makes the process easier and prevents sticking later.

Place the bread slices in a large bowl. Pour the milk over them. Let the bread soak for several minutes. This creates a soft mixture that helps keep the meatloaf tender and moist.

Add the diced onion, eggs, parsley, salt, pepper and seasoned salt to the soaked bread. Stir everything together until the ingredients are evenly combined and well distributed throughout the mixture.

Add the ground beef to the bowl. Use clean hands or a spoon to mix gently. Do not overmix. Mixing too much can make the meatloaf dense instead of tender.

Transfer the meat mixture to the prepared pan. Shape it into a loaf if using a baking sheet. Press gently so it holds together while baking but remains light.

In a small bowl, combine ketchup, brown sugar, mustard powder and hot sauce. Stir until smooth. This glaze adds a sweet and tangy flavor that makes the meatloaf extra delicious.

Spread one-third of the glaze evenly over the top of the meatloaf. Use a spoon or brush to cover the surface. This layer starts building flavor while baking.

Place the meatloaf in the oven and bake for 45 minutes. During this time, the meat cooks through while the flavors blend together beautifully.

Remove the meatloaf from the oven carefully. Spread another layer of glaze over the top. Return it to the oven and continue baking for 15 more minutes.

Remove the meatloaf from the oven when the internal temperature reaches 160°F (71°C). Let it rest for 10 minutes before slicing. Resting helps keep the juices inside the meat.